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Alzheimer's Disease

Alzheimer's is a 21st century disease that affects

35 million elderly people globally. It's a neuro degenerative disease that usually causes dementia. It has been traced down to the APP gene, and amyloid-beta peptides that form on the outside of neurons. Many attempts have been made to target amyloid-beta or the enzymes involved in it's formation, however the newest hope seems to be in CRISPR. A study from Iceland has proven this by finding the particular mutation in the APP gene. Although 420,000 people are expected to develop Alzheimers today, with CRISPR, the number can be reduced to 120,000. [E.9]

How It Is Put Into Commision!

"Dementia - A group of thinking and social symptoms that interferes with daily function"  ~ Mayo Clinic Staff

In embryos, if we conduct gene editing we are

capable of preventing a variety of diseases, including Alzheimer's. By finding and producing a gene editing technique to stop the APP mutation, we can thus stop cellular enzymes that cut amyloid-beta fragments, from their precursor protein. This was proven in cultured human cells through expermients. The plan is to insert a protective allele into embryos dramatically halting the lifetime risk of children developing Alzheimer's as adults, through genetic variation. [E.9]

What To Remember About Alzheimer's

© 2016 by Thomas Abbott and Chubi Yambao. Proudly created with Wix.com

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